THURSDAY, March 5, 2020 — Habitual supplementation with fish oil is associated with a reduced risk for cardiovascular disease (CVD) outcomes and all-cause mortality, according to a study published online March 4 in The BMJ.

Zhi-Hao Li, from Southern Medical University in Guangzhou, China, and colleagues examined the correlations of habitual fish oil supplementation with CVD and mortality in a prospective cohort study involving 427,678 men and women aged 40 to 69 years who were enrolled between 2006 and 2010 and were followed through 2018.

Overall, 31.2 percent of the participants reported habitual use of fish oil supplements at baseline. The researchers found that for habitual users of fish oil versus nonusers, the multivariable adjusted hazard ratios were 0.87 for all-cause mortality, 0.84 for CVD mortality, and 0.93 for incident CVD events. For CVD events, those with prevalent hypertension seemed to have a stronger association.

“These findings indicate that habitual use of fish oils is associated with a marginal benefit for CVD events in the general population, supporting their use for the prevention of mortality from all causes and CVD,” the authors write. “Future studies are needed to examine the extent to which the dose of fish oil supplements influences the ability to achieve a clinically meaningful effect.”

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Posted: March 2020



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